Pharmalogical Screening Services
We offer the following cell based assays (Oncology & Immunology) on a contract research basis:
Screening compounds for anti-tumor activity:
- Proliferation studies on murine or human tumor cell lines
- Cytotoxicity studies on normal cells
- Selectivity studies on normal and tumor cells
- Myelotoxicity studies on myeloid precursors
- Mechanism of action studies
Assays to evaluate the immunomodulant activity of compounds:
- Studies on the tumor response against T dependent or T independent antigens
- Proliferation studies on Lymphocytes stimulated with mitogens
- Studies on the phagocytosis of macrophages
- Studies on the release of specific cytokines by immuno-competent cells
New Arrays
- Hormone refractory prostate cancers
- Prostate cancer bone metastases
- NSCLC primary & matched distant metastases
- Pancreatic cancer primary & matched metastases
- Alzheimer's disease
Contract Research Services
- Large scale multi-tumor (>3500 donor samples) & normal human tissue (>600 donor samples) analysis
- Large scale tumor prognosis analysis
- Large-scale analysis of primary tumors and matched metastases
- GLP tissue cross reactivity studies (human, cynomolgus monkey, rat)
- Gene amplification prognosis studies by FISH
- Pharmacological screening services (cell based assays)
- Cardiotoxicity screening of compounds using EHT (engineered heart tissues)