Innovative, Inventive...
Giving clinical significance to molecular targets.
TriStar Tissue Micro Arrays enable the simultaneous analysis of thousands of human tissue samples in a single experiment under uniform conditions.
Tissue Micro Arrays are ideally suited for further validation of data regarding individual genes of particular clinical relevance detected by cDNA array analysis.
TriStar's unique tissue micro array platform utilizes high-throughput molecular pathology to provide clinically relevant data related to molecular target expression/amplification in thousands of human normal and diseased tissues. Focus areas include Cancer and Neurodegenerative diseases. Tissues are collected in accordance with applicable laws and regulations. Repositories are located in Hamburg (Germany), Catania (Italy) and Washington DC.
Our repository of over 60,000 arrayed human cancer & normal tissues with extensive clinical data is by far the largest of its kind in the world today. We provide standard and customized high-density tissue arrays, formalin fixed and frozen (OCT) tissue blocks and the following contract research services:
- High density tissue arrays / tissue slides with annotated information covering prognosis, treatment & response
- Contract research services for the validation of molecular targets in over 120 different cancers and 76 types of human normal tissues by IHC/FISH
- Relating target expression to prognosis, treatment and response in 12 prevalent cancer types, up to 3500 donor samples each.
- Tissue cross-reactivity screening (GLP-FDA & non-GLP)
- Pharmacological screening services (cell based assays)
- Screening compounds for cardiotoxicity using Engineered Hear Tissues (EHT)
New Arrays
- Hormone refractory prostate cancers
- Prostate cancer bone metastases
- NSCLC primary & matched distant metastases
- Pancreatic cancer primary & matched metastases
- Alzheimer's disease
Contract Research Services
- Large scale multi-tumor (>3500 donor samples) & normal human tissue (>600 donor samples) analysis
- Large scale tumor prognosis analysis
- Large-scale analysis of primary tumors and matched metastases
- GLP tissue cross reactivity studies (human, cynomolgus monkey, rat)
- Gene amplification prognosis studies by FISH
- Pharmacological screening services (cell based assays)
- Cardiotoxicity screening of compounds using EHT (engineered heart tissues)